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Individuals and families covered by HSA-qualified, high-deductible health plans could see significant reductions in their out-of-pocket expenditures over the next 14 months as generic versions of seven of the world’s 20 best-selling drugs, including cholesterol fighter Lipitor and blood thinner Plavix, hit the market.

According to the London research firm EvaluatePharma Ltd, best selling drugs with about $255 billion in global annual sales will go off patent between now and 2016. Generic competition is expected to slash the cost to patients and companies that provide health benefits.

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