LAKE FOREST, Ill. (AP) — Drug and medical device maker Hospira Inc. said Tuesday it posted a $214 million fourth-quarter loss, as the shutdown of one of its plants reduced its sales for the quarter.

But excluding one-time charges, the company's results beat Wall Street predictions and Hospira shares jumped $2.27, or 6.6 percent, to $36.49 in heavy midday trading, after peaking at $37.70 earlier in the day.

Hospira's loss amounted to $1.30 per share and compared with a profit of $60.6 million, or 36 cents per share, in the year-earlier period. Excluding one-time items, the company said it posted an adjusted profit of 51 cents per share for the recent quarter.

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