(Bloomberg) — With Aetna Inc. and Humana Inc. pairing off, pressure is mounting on other major health insurers to make their own deals.

Cigna Corp.'s tie-up with Anthem Inc. could be the next one on deck. Cigna rebuffed a bid from Anthem last month, and both were said to have been interested in Humana. But after the acquisition announced Friday, their options just got narrower.

"It paves the way for Cigna and Anthem," Ana Gupte, an analyst at Leerink Partners in New York, said by phone. "Cigna has fewer choices at this point."

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