The nation's most influential science advisory group will tell Congress today that the U.S. pharmaceutical market is not sustainable and needs to change.

"Drugs that are not affordable are of little value and drugs that do not exist are of no value," said Norman Augustine, chair of the National Academies of Sciences, Engineering and Medicine's committee on drug pricing and former CEO of Lockheed Martin Corp.

The report, "Making Medicines Affordable: A National Imperative," identifies eight steps to cut drug prices. It also provides a list of specific "implementation actions" for various federal agencies, including Congress, the Federal Trade Commission and the U.S. Departments of Justice and Health and Human Services.