"By the 46th day after his appeal, Hartford had not determined McQuillin's benefits nor extended its review time."

Judges agreed with the plaintiffs' argument over who should pay for medications, but it did not apply retroactively, thus denying her relief.

The DOJ and states appealing the ruling objected to the fact that the plan included releases of liability for members of the Sackler family.

The $4.5 billion would be paid over nine years for prevention, treatment and recovery programs related to opioid addiction.

The settlement does not cancel the trial, but it does remove one of the most high-profile defendants in the case.

The rule would have taken effect Tuesday.