For the drug industry, building a better pain pill is a problem.
Pharmaceutical companies have introduced new medicines to treat dependence, reverse overdoses, and deal with opioids' side effects. But few effective and economically viable alternatives to addictive painkillers have emerged from the laboratory.
That's because of broken incentives, according to economists and industry experts. The payment policies of insurers and government health programs, along with pressure from investors, have encouraged drugmakers to treat the symptoms of the opioid epidemic but discouraged innovations that might get to the root of the problem.
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