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This Tuesday, May 8, 2007, file photo shows the Purdue Pharma logo at its offices in Stamford, Conn. The company is facing some 2,000 lawsuits in the United States over its role in unleashing an addiction crisis that has claimed 400,000 lives. More than a dozen defendants face numerous claims at next month’s trial, which will take place in Cleveland.  (AP Photo: Douglas Healey, File)

Manufacturers of prescription opiates lost a key ruling Monday involving public nuisance claims as pressure against them mounts ahead of a closely watched trial next month.

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