As it tracks yet more COVID-19 variants, the Centers for Disease Control and Prevention (CDC) recently reported that — at the end of 2022 — about one in four people 16 years of age and older in the United States had yet to contract the virus. That means 77.5% had antibodies from at least one prior infection. What’s more, 96.7% had antibodies from either getting vaccinated, surviving a bout with COVID, or a combination of both.

This new information is based on final figures from the CDC’s “2022 Nationwide COVID-19 Infection- and Vaccination-Induced Antibody Seroprevalence” study. The percentage of people with antibodies against a virus in their blood is known as seroprevalence. Beginning in January 2022, the longitudinal study of approximately 143,000 blood donors tracked seroprevalence estimates during four three-month periods.

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