The case against the megamerger between Anthem and Cigna is slated to begin today, with the government hoping to block the deal.

Anthem Inc.’s proposed merger with Cigna Corp. would reduce health-care competition and raise costs for consumers, U.S. antitrust lawyers will argue Monday when the government goes to court to block the transaction.

Their $48 billion merger — the biggest in the history of the American health-insurance industry — would likely give the enlarged company the power to raise prices for insurance, cut payments to doctors and reduce the quality of service, the Justice Department has said in court papers.

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