Cigna logo on building Questions about the future of the drug-middleman business are weighing on Cigna as it works to complete the deal. (Photo: AP)

The top executive of health insurer Cigna Corp., which recently agreed to take over one of the largest pharmacy-benefit managers, said he’s ready for changes in how prescription drugs are priced and sold in the U.S.

“The way rebates function in the marketplace are a manifestation of the way the pharmaceutical manufacturers have worked for quite some time,” Cigna Chief Executive Officer David Cordani said in an interview. “That will change and evolve.”

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