Pills and handcuffs A convictionon federal fraud, racketeering and kickback charges could send JohnKapoor and four other ex-Insys managers to prison for as long as 25years. (Photo: Shutterstock)

The first prosecution of a pharmaceutical company chiefexecutive tied to opioid overdoses begins this week, when InsysTherapeutics Inc.'s John Kapoor goes on trial. The fallout may joltan industry facing steep penalties for its own role in the crisis.

Kapoor, 75, is accused of masterminding illegal marketing tactics that contributed to anepidemic of addiction and death. A onetime billionaire who rosefrom modest means in India, he's on trial for using speakers' fees,dinners and cash to lure doctors into prescribing a highlyaddictive opioid painkiller meant solely for cancer patients.

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