Bag of blood and test vials Scientists have been running controlled anti-aging and rejuvenation tests for a century—but on rodents, not people. (Photo: Shutterstock)

In 2016, a tiny startup announced an experiment that seemed equal parts medieval sorcery and science fiction: It would inject older people with the blood plasma of young donors in a bid to slow aging.

For three years, Ambrosia Chief Executive Officer Jesse Karmazin charged patients $8,000 to infuse one liter of plasma as part of an unorthodox, crowd-funded clinical trial. Karmazin promised extraordinary results—going so far as to proclaim in media interviews that his treatment “comes pretty close” to immortality.

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