Drug vials Payment options for the drug include spreading out the costs over time, refunds for patients whose treatment fails and discounts for insurers that provide swift coverage. (Photo: Shutterstock)

A potential cure for a lethal childhood disorder — the first of its kind in the U.S. — is hitting the market at a cost of $2.1 million, paving the way for more therapies that bring dramatic benefits for patients, along with challenges for health-care systems.

The U.S. Food and Drug Administration on Friday approved Novartis AG’s Zolgensma, a gene therapy targeting children under two years old who have a severe illness called spinal muscular atrophy. The Swiss drugmaker said it’s offering novel payment options, including spreading out the costs over time, refunds for patients whose treatment fails and discounts for insurers that provide swift coverage.

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