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Blue Shield of California expects to save $500 million in annual drug costs by replacing most of CVS Health’s pharmacy benefit manager services with five different partners by January 2025. The insurer serves about 4.8 million members.

Amazon Pharmacy will offer at-home drug delivery, and Mark Cuban’s Cost Plus Drug Company will provide access to low-cost medications through retail pharmacies. Another company, Abarca Health, will process drug claims. Blue Shield will retain CVS Caremark for its specialty pharmacy services, which provide specialized therapies and counseling to patients suffering from complex disorders.

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