After a $14,000 price tag for its cholesterol fighter Repatha proved more than insurers were willing to pay, the company is taking a more conservative approach with its latest blockbuster.

Elizabeth Holmes claimed her now-infamous medical-testing startup Theranos Inc. would change medicine with a single drop of blood.

The announcement "will set an important precedent in the ongoing drug pricing debate here in the U.S.," says one analyst.

Bob Hugin helped build a pharmaceutical powerhouse. As he seeks to claim the seat of an embattled Democratic senator in New Jersey, that legacy could be both a blessing and a burden.

For small, rural hospitals across the country, labor, drug, and technology costs are increasing faster than the revenue and patients unpaid debts are on the rise.