The Health Care Select Sector SPDR Fund, known by its ticker XLV, remains up more than 10 percent this year, while the S&P 500 Index erased gains. (Photo: Shutterstock)

(Bloomberg) –Health-care investors may have to be a bit more selective than they're used to in 2019.

With U.S. health stocks poised to wrap up their second straight year of outperforming the broader market, the focus on hunting for innovation and next year's winners is even more in vogue after recent market volatility.

Small- to mid-cap biotechnology darlings that saw shares surge amid a seemingly never-ending bull market have been punished and high-flying device makers ran cold, causing some investors to sell out of positions hand over fist.

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